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TRIAZINETRIONE DERIVATIVES AND THEIR USE AS MODULATORS OF NEUROTROPHIN RECEPTOR AND RECEPTOR TYROSINE KINASES
专利权人:
ALZECURE PHARMA AB
发明人:
Gunnar NORDVALL,Pontus FORSELL,Johan SANDIN
申请号:
US16471923
公开号:
US20200113910A1
申请日:
2017.12.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to anew use of 4-phenoxy-phenyl-1,3,5-triazine derivatives or pharmaceutically acceptable salts thereof, according to formula I, wherein R1, R2 and U have meanings as provided in the description, as medicaments for the treatment and/or prevention of diseases characterised by impaired signalling of neurotrophins and/or other trophic factors. In particular, the invention relates to the treatment of such diseases in patients with the Val66Met mutation in the brain-derived neurotrophic factor gene.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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