SWAYZE ERIC E.,THAZHA P. PRAKASH,PUNIT P. SETH,MARK J. GRAHAM
申请号:
NZ63151214
公开号:
NZ631512A
申请日:
2014.05.01
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Discloses a compound comprising a modified oligonucleotide and a conjugate group, wherein the modified oligonucleotide consists of 20 contiguous nucleobases complementary to an equal length portion of nucleobases 3901 to 3920 of SEQ ID NO: 1, wherein the nucleobase sequence of the modified oligonucleotide is at least 80% complementary to SEQ ID NO: 1; and wherein the conjugate group and sequences are as defined in the complete specification.