Swayze Eric E.,Thazha P. Prakash,Punit P. Seth,Mark J. Graham
申请号:
NZ63153714
公开号:
NZ631537A
申请日:
2014.05.01
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
Disclosed is a compound comprising a modified oligonucleotide and a conjugate group, wherein the modified oligonucleotide consists of 20 contiguous nucleobases complementary to an equal length portion of nucleobases 3533 to 3552 of SEQ ID NO: 3 (as defined in the specification), wherein the nucleobase sequence of the modified oligonucleotide is at least 80% complementary to SEQ ID NO: 3.