The present invention discloses a system and method to measure the pulse pressure signals, which inflates and deflates at least one air bag to detect pulse pressure signals of a human limb. The system comprises a detection device and a host device. The detection device is place on an artery of a human limb and includes one or more air bags. The host device controls inflation and deflation of the air bags, measures pressure variation of the air bags, and records and analyzes pulse pressure signals. The system and method of the present invention can simulate the three-finger technique of pulse diagnostics of the traditional Chinese medicine and provide physicians with more reliable pulse-diagnostics information.一種脈搏壓力訊號的量測系統及其量測方法,利用至少一氣囊在充氣及洩氣間的體積膨脹,感測人體四肢之脈壓訊號。量測系統包括一感測裝置與一主機裝置,感測裝置位於一人體四肢動脈上,且包括一個或一個以上的氣囊。主機裝置控制感測裝置內氣囊的充氣及洩氣,並且藉由量測其囊內壓力的變化,進行脈壓訊號的紀錄與分析。應用此種量測系統及其量測方法,可簡易模擬醫者三指按壓血管之技巧,並提供給醫師較精確的脈診判斷與病理參考。10...感測裝置12...氣囊16...定位架20...主機裝置30...氣管204...儲存裝置206...通訊裝置210...顯示裝置