Hu Jing Hua,Virtanen Antti Leo Oskari,Miller Cary James,Campbell John Lewis Emerson,Moss Adam Roger
申请号：
US201715836078
公开号：
US2018164305(A1)
申请日:
2017.12.08
申请国别(地区):
美国
年份:
2018
代理人:
摘要：
The present invention relates to systems and methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a method includes determining a first concentration of an analyte at a first immunosensor from a reaction of a signal agent with a first complex of signal antibodies, the analyte, and capture antibodies immobilized on a surface of the first immunosensor, determining a second concentration of the analyte at a second immunosensor from a reaction of the signal agent with a second complex of the signal antibodies, the analyte, and capture antibodies immobilized on magnetic beads that are localized on or near a surface of the second immunosensor via a magnetic field, determining a weighted average of the first concentration and the second concentration, and comparing the weighted average to a predetermined crossover concentration point or zone.
