Hu Jing Hua,Virtanen Antti Leo Oskari,Potter Eric Edward,Smith James T.K.,Miller Cary James,Campbell John Lewis Emerson,Moss Adam Roger
申请号：
US201715836135
公开号：
US2018164306(A1)
申请日:
2017.12.08
申请国别(地区):
美国
年份:
2018
代理人:
摘要：
The present invention relates to systems and methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device includes a first immunosensor including an immobilized layer of capture antibodies configured to bind to a first complex of signal antibodies and cardiac troponin such that a second complex of the first complex and the immobilized layer of capture antibodies is localized on or near the first immunosensor. The device further includes a second immunosensor having a magnetic field disposed locally around the second immunosensor. The magnetic field is configured to attract magnetic beads such that a third complex of the first complex and capture antibodies immobilized on the magnetic beads is localized on or near the second immunosensor sensor.
