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SOLUTION ANTI-TRICHOPHYTIQUE A USAGE EXTERNE
专利权人:
MEIJI SEIKA PHARMA CO.; LTD.
发明人:
FURUTA, YOSHIKO,KOMATSU, KAZUKI,KAYA, ARPANSIREE,TAKAHATA, SHO,TABATA, YUJI
申请号:
CA2879846
公开号:
CA2879846A1
申请日:
2013.07.30
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention provides a solution for external use having antitrichophytosis activity and high nail permeability. A solution for external use for preventing or treating trichophytosis, the solution containing a coating formation agent, and a compound represented by the general formula [in the formula, R1 represents a hydrogen atom, C1-6 alkyl, or trilfuoromethyl; R2 represents a hydrogen atom, C1-6 alkyl, halogen, -COO (C1-6 alkyl), or (CH2)1-3COOR (R represents a hydrogen atom or C1-6 alkyl); R3 represents a hydrogen atom, C1-6 alkyl, amino, trifluoromethyl, or OR (R represents a hydrogen atom or C1-6 alkyl); R4 represents a hydroxyl group; R5 represents a hydrogen atom, C1-6 alkyl, hydroxyl group, or halogen; R6 represents a hydrogen atom, C1-6 alkyl, trifluoromethyl, halogen, amino, -NRaRb, nitro, hydroxy C1-6 alkyl, -CONRaRb, -COO (C1-6 alkyl), -COOH, -(CH2)1-3COOR, or ORa (R represents a hydrogen atom or C1-6 alkyl, and Ra and Rb may be the same or different and represent a hydrogen atom, C1-6 alkyl, or C1-6 acyl); R7 is a hydrogen atom, C1-6 alkyl, -OR (R represents a hydrogen atom or C1-6 alkyl), or halogen; and R8 represents a hydrogen atom, C1-6 alkyl, hydroxyl group, amino, or nitro] or a salt thereof.
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