James R. Baker, Jr.;Larry A. Sternson;Deborah Ladenheim;James R. Baker;David Repp; Jr.
发明人:
James R. Baker, Jr.,Larry A. Sternson,David Repp,Deborah Ladenheim
申请号:
US13126633
公开号:
US09017644B2
申请日:
2009.11.09
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to dendrimer compositions configured for treating inflammatory disorders and autoimmune disorders, and related methods of synthesis. Specifically, the present invention relates to methods for treating rheumatoid arthritis with PAMAM dendrimers having functional ligands configured for treating rheumatoid arthritis (e.g., therapeutic agents, pro-drugs, targeting agents, trigger agents, imaging agents) (e.g., methotrexate).