A method and an article of manufacture are disclosed for exchanging heat with a human body part to reduce fever, reduce localized swelling, warm up feet, cool down the body, increase body core temperature, and the like. A double walled water-tight article of clothing, such as a boot or a glove, may include a fluid inlet and outlet. A single walled but water-tight article of clothing may be used around a body part and allow the water to contact the skin inside the article of clothing for more rapid and direct heat exchange. Pumps, heating or cooling elements, thermometers or other devices may be included with the article of clothing. The article of clothing may be compartmentalized to concentrate the fluid around a particular body part. Multilayered articles of clothing are also disclosed to inject a thermal gas into a heat exchange space to cool or warm a user.