THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS; REPRESENTED BY THE SECRETARY;THE UNITED STATES OF AMERICA;THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
ERICKSON, JOHN W.,GULNICK, SERGEI V.,MITSUYA, HIROAKI,GHOSH, ARUN K.
申请号:
CA2872424
公开号:
CA2872424C
申请日:
1999.06.23
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Disclosed are compounds of the formulas:(see formula IA)and(see formula IB)wherein R1, X, Y, Z, m, n, R3, R5, and R6 are herein defined, or apharmaceutically acceptablesalt thereof, for use in the preparation of a medicament for treating a humanimmunodeficiencyvirus (HIV) infection in an antiretroviral treatment-experienced mammal, forinhibiting a mutantretroviral infection in a mammal infected with a mutant retrovirus, and forpreventing thedevelopment of drug resistance in an HIV-infected mammal.