An implant is manufactured by first coating a bioactive material on a surface of the implant and second coating hydrogel including a bioactive material on a surface of the first-coated implant. A speed of emission of the bioactive material is adjusted by the second coating. Thus, an effect of a growth factor is increased by adjusting a speed of emission of bone morphogenetic protein. Accordingly, hydrophilic property of an inorganic biomaterial is improved and attachment and differentiation of a cell is improved. Thus, an implant having a higher survival rate and capable of inducing rapid osseointegration is manufactured.一種植入物係藉由下列製造：一第一塗覆，塗覆一生物活性材料於該植入物的一表面上；以及一第二塗覆，塗覆包含一生物活性材料之水凝膠(hydrogel)於該經第一塗覆之植入物的一表面上。該生物活性材料之釋放速度係藉由該第二塗覆而調整。因此，生長因子之效應係藉由調整骨形態形成蛋白之釋放速度而增大。相應地，無機生物材料之親水性得以增加，且細胞之附著及分化得以提高。因此，製得一具有更高存活率且能夠引發快速骨整合的植入物。
