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CONTRAST MEDIA WITH LOW IODINE CONCENTRATION FOR X-RAY VISUALIZATION AND METHOD OF X-RAY VISUALIZATION
专利权人:
ДжиИ Хелткер АС
发明人:
НЬЮТОН Бен,ТАНИНГ Миккель,ВЕЛД Дир-Ян Ин'т,ЛАНГСЕТ Карина,ЭВАНС Пол Майкл,ВЕЛД Дир-Ян Инт
申请号:
RU2014125447
公开号:
RU2014125447A
申请日:
2013.01.10
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. X-ray composition containing yoforminol and a pharmaceutically acceptable carrier or excipient, where the composition contains iodine in a concentration of 10-200 mg I / ml and sodium ions in a concentration of 70-120 mm. The composition of claim 1, further comprising calcium ions in a concentration of 0.5-1.3 mM. 3. The composition of claim 1, further comprising potassium and / or magnesium ions. 4. The composition of claim 1, wherein the total volume for administration to the body is from 1 to 250 ml. A composition according to claim 1, wherein the iodine concentration is approximately 160 mg I / ml, the sodium concentration is approximately 82 mm and the calcium concentration is 0.7 mm. A composition according to claim 1, wherein the iodine concentration is approximately 200 mg I / ml, the sodium concentration is approximately 73 mm and the calcium concentration is 0.6 mm. The composition according to any one of paragraphs. 1-6 for use in the method of x-ray examination, including the introduction of the composition into the body; exposure to the body with a dose of x-ray radiation; study of the body using a diagnostic device and compiling the study data. 8. An X-ray examination method, comprising administering to the body a composition containing yoforminol and a pharmaceutically acceptable carrier or excipient, wherein the composition contains iodine at a concentration of 10-200 mg I / ml and sodium ions at a concentration of 70-120 mM; exposure to the body with a dose of x-ray radiation; study organism using a diagnostic device and compiling research data. 9. The method according to claim 8, enhancing the contrast effect of yoforminol, wherein said radiation dose has an average energy spectrum substantially corresponding to the k-edge of iodine. The method of claim 8, wherein the dose of x-ray radiation is provided with voltage energy1. Рентгеновская композиция, содержащая йоформинол и фармацевтически приемлемый носитель или эксципиент, где композиция содер
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