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PROCESS FOR GRANULATING SEVELAMER CARBONATE
专利权人:
发明人:
申请号:
EP16705210.9
公开号:
EP3261624A1
申请日:
2016.02.19
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present disclosure provides a pharmaceutical composition comprising of a polyallylamine polymer or pharmaceutically acceptable salts thereof excipient based hydrous granules and optionally moisture retaining agents. The present disclosure also provides process embodiments for preparation of the pharmaceutical compositions comprising of modified moisture activated granulation technique. Polyallylamine polymers used are Sevelamer, Colesevelam or pharmaceutically acceptable salts thereof, preferably Sevelamer HCl, Sevelamer carbonate or Colesevelam HCl. The Tablet according to the present disclosure comprising of polyallylamine polymer which can be prepared by using modified moisture activated granulation technique, by adding one or more excipient based hydrous granule(s), contacting the said hydrous granule(s) with polyallylamine polymer and optionally adding one or more moisture retaining agents and lubricant(s) resulting in the compression into a tablet form using suitable tools.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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