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SEMI-SOLID COMPOSITIONS AND PHARMACEUTICAL PRODUCTS
专利权人:
ФотоКьюэр АСА (NO)
发明人:
СТЕНСРУД Грю (NO)
申请号:
RU2011150919/15
公开号:
RU2011150919A
申请日:
2010.06.11
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A semi-solid pharmaceutical product for use in the photodynamic treatment of cancerous, precancerous and noncancerous conditions of the female reproductive system, anus and penis, comprising: a) an active ingredient selected from 5-ALA, a precursor of 5-ALA or a derivative of 5-ALA and their pharmaceutically acceptable salts; b) one or more triglycerides; c) possibly one or more viscosity enhancers. 2. The semi-solid pharmaceutical product of claim 1, wherein said active ingredient is a 5-ALA derivative, preferably 5-ALA ester or a pharmaceutically acceptable salt thereof. The semi-solid pharmaceutical product according to claim 1, wherein said active ingredient is a compound of formula I or a pharmaceutically acceptable salt thereof, where R 1 represents a substituted or unsubstituted alkyl group; and each R independently represents a hydrogen atom or an R.4 group. The semi-solid pharmaceutical product of claim 1, wherein the one or more triglycerides are glycerol triglycerides and 3 identical or different C-fatty acids, more preferably 3 identical or different C-fatty acids, even more preferably 3 identical or different C-fatty acids and most preferably 3 identical or different C-C fatty acids. 5. The semi-solid pharmaceutical product of claim 1, wherein the one or more triglycerides are liquid triglycerides and one or more viscosity enhancers are present. The semi-solid pharmaceutical product according to claim 5, where one or more viscosity enhancers selected from cellulose and its derivatives, synthetic polymers, polyethylene glycols, vegetable gums, starch and derivatives1. Полутвердый фармацевтический продукт для применения в фотодинамическом лечении раковых, предраковых состояний и нераковых состояний женской репродуктивной системы, ануса и пениса, содержащий:а) активный ингредиент, выбранный из 5-ALA, предшественника 5-ALA или производного 5-ALA и их фармацевтически приемлемых солей;б) один или более триглицеридов;в) возможно одного или более усилителей
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