The present invention discloses a dry powder inhaler (1) comprising a housing (10, 10) with: - an air supply channel (100) fluidly connected with an air inlet opening (101, 102) of the housing (10, 10) - a single circulation chamber (140) for deagglomeration of a powder formulation, wherein the circulation chamber (140) is fluidly connected and/or connectable with the air supply channel (100), and wherein the circulation chamber (140) is arranged downstream of the air supply channel (100) - a mouthpiece (13) fluidly connected with the circulation chamber (140) via an outlet (143) of the circulation chamber (140), wherein the mouthpiece (13) is arranged downstream of the circulation chamber (140). The dry powder inhaler according to the present invention is characterized in that the dry powder inhaler (1) contains only one single dose of the powder formulation and in that during storage of the powder formulation the powder formulation is in direct contact with the housing (10, 10).