The invention relates to an injection device, preferably of the pre-filled type. The injection de- vice comprises a housing structure which supports a piston rod drive for driving a preservative containing pharmaceutical liquid drug out from a cartridge which is axially movable a small distance in relation to the housing structure. The injection device further comprises a movable needle hub securing a needle cannula and a rotatable needle shield covering the needle cannula. The needle hub is movable in a proximal direction to insert the proximal part of the needle cannula through the pierceable septum and into the interior of the cartridge, and the needle shield which carries a cleaning reservoir containing a predetermined volume of the preservative containing pharmaceutical liquid drug for cleaning at least the distal tip of the needle cannula between subsequent injections, is rotatable from a first position to a second position. Further, transfer means are provided which transfers axial and linear movement of the needle hub to a helical movement of a transfer element which moves the cartridge proximally relatively to the housing structure to thereby force liquid preservative containing drug from the interior of the cartridge through the lumen of the needle cannula and into the cleaning reservoir.L'invention concerne un dispositif d'injection, de préférence du type prérempli. Le dispositif d'injection comprend une structure de boîtier qui supporte un entraînement de tige de piston pour entraîner un médicament liquide pharmaceutique contenant un conservateur hors d'une cartouche qui est axialement mobile à une petite distance par rapport à la structure de boîtier. Le dispositif d'injection comprend en outre un raccord d'aiguille mobile fixant une canule d'aiguille et une protection rotative d'aiguille recouvrant la canule d'aiguille. Le raccord d'aiguille est mobile dans une direction proximale pour insérer la partie proximale de la canule d'aiguille à travers le se
