Nicolas Anfossi,Laurent Gauthier,Yannis Morel,Alessandro Moretta,Silvia Parolini,Benjamin Rossi
申请号:
US14924786
公开号:
US09828427B2
申请日:
2015.10.28
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides antigen-binding proteins capable of binding to KIR3D polypeptides. The antibodies have increased activity in the treatment of disorders characterized by KIR3DL2-expressing cells, particularly CD4+ T cells, including malignancies such as Mycosis Fungoides and Sézary Syndrome.