Nicolas Anfossi,Laurent Gauthier,Yannis Morel,Alessandro Moretta,Silvia Parolini,Benjamin Rossi
申请号:
US13145224
公开号:
US20120064081A1
申请日:
2010.01.15
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides antigen-binding proteins capable of binding to KIR3D polypeptides. The antibodies have increased activity in the treatment of disorders characterized by KIR3DL2-expressing cells, particularly CD4+ T cells, including malignancies such as Mycosis Fungoides and Sézary Syndrome.