Kayvan Niazi,Shahrooz Rabizadeh,Anne-Laure Le Ny,Oleksandr Buzko,Justin Golovato,Patrick Soon-Shiong
申请号：
US13622807
公开号：
US08633198B1
申请日:
2012.09.19
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Antiviral compositions and methods are contemplated that are especially effective in the treatment and prevention of influenza A viruses. Also presented are cellular assays to identify small molecule compounds having antiviral properties, particularly as it relates to detection of influenza A RNA-dependent RNA polymerase activity in a mammalian cell independent of other influenza A components. Preferred assays allow for identification of viral replication inhibitors that do not disrupt normal cellular activity.
