Niazi, Kayvan,Rabizadeh, Shahrooz,Le Ny, Anne-Laure,Buzko, Oleksandr,Golovato, Justin,Soon-Shiong, Patrick
申请号:
AU2016273938
公开号:
AU2016273938B2
申请日:
2016.12.15
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2016273938B220180823.pdf#####ABSTRACT Antiviral compositions and methods are contemplated that are especially effective in the treatment and prevention of influenza A viruses. Also presented are cellular assays to identify small molecule compounds having antiviral properties, particularly as it relates to detection of influenza A RNA-dependent RNA polymerase activity in a mammalian cell independent of other influenza A components. Preferred assays allow for identification of viral replication inhibitors that do not disrupt normal cellular activity.