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Composés lipidiques oxydés et leurs utilisations
专利权人:
Vascular Biogenics Ltd.
发明人:
申请号:
EP14188368.6
公开号:
EP2826370A3
申请日:
2009.11.05
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Novel oxidized lipids are provided herein, as well as methods for producing same, and uses thereof in treating or preventing an inflammation associated with endogenous oxidized lipids and related conditions.wherein(i) A1, A2 and A3 are each independently selected from the group consisting of O and S;(ii) R1 is an alkyl chain 2-28 carbons in length; and(iii) R2 is selected from the group consisting of (3-carboxy)propyl and (2-carboxy)ethyl; and(iv) R3 is selected from the group consisting of H, acyl, alkyl, phosphate, phosphocholine, phosphoethanolamine, phosphoethanolamine-N-glutaric acid, and phosphoserine, and phosphoinositol.
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