The present invention provides a manufacturing method of detox functional juice and detox functional juice, which improve a fiber uptake ratio by juice mixing vegetables and fruits with an optimal ratio to detoxify a body, thereby activating an intestinal immune function. The manufacturing method of detox functional juice comprises: a first step of preparing the vegetables with cabbage, carrot and broccoli, preparing the fruits with apples, bananas, tomatoes and grapefruits, and washing the vegetables and fruits a second step of putting the washed vegetables and fruits into a nonwoven fabric, and extracting by putting the nonwoven fabric into an extractor a third step of sterilizing the extracted juice with temperature and pressure and a fourth step of vacuum-packing the juice into a pouch after secondary filtration.본 발명은 해독주스의 제조방법 및 해독주스에 관한 것이다. 본 발명은, 양배추, 당근, 브로콜리로 야채를 준비하며, 사과,바나나,토마토,자몽 의 과일을 준비한 뒤, 상기 야채와 과일을 각각 세척하는 제 1단계와, 부직포에 상기 세척된 야채와 과일을 부직포에 담아 추출기에 넣고 추출하는 2단계와, 추출된 주스를 온도와 압으로 살균처리 하는 3단계와, 2차 여과후 파우치에 진공포장하는 4단계를 포함한다.