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USE OF INDOLE DERIVATIVES AS NURR-1 ACTIVATORS FOR TREATING PARKINSON S DISEASE
专利权人:
LABORATOIRES FOURNIER S.A.
发明人:
BOUBIA BENAISSA,VAN VLIET BERNARD JOHANNES,DEN HARTOG JACOBUS ANTONIUS JOSEPH,MCCREARY ANDREW,TALLANDIER MIREILLE,VAN DONGEN MARIA JOHANNA PETRONELLA,POUPARDIN-OLIVIER OLIVIA
申请号:
SI200930209
公开号:
SI2300424T1
申请日:
2009.07.09
申请国别(地区):
SI
年份:
2012
代理人:
摘要:
The present invention relates to a compound derived from indole, especially a therapeutically useful compound, characterized in that it is selected from compounds of formula (I) in which R1 represents a halogen or a trifluoromethyl group, R2 represents a hydrogen atom or a C1-C4 alkyl group, R3 represents an isopropyl (1-methylethyl) group or a tert-butyl (1,1-dimethylethyl) group and n=3 or 4 and pharmaceutically acceptable salts of said compounds of formula (I). Application: Treatment of neurodegenerative diseases and more particularly of Parkinsons disease.
来源网站:
中国工程科技知识中心
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