BENAÏSSA BOUBIA,VAN VLIET,DEN HARTOG,MCCREARY,MIREILLE TALLANDIER,MARIA JOHANNA PETRONELLA VAN DONGEN,OLIVIA POUPARDIN-OLIVIER
申请号：
MYPI 2011000084
公开号：
MY155959A
申请日:
2009.07.09
申请国别(地区):
MY
年份:
2015
代理人:
摘要：
USE OF INDOLE DERIVATIVES AS NURR-1 ACTIVATORS, FOR THE TREATMENT OF PARKINSON’S DISEASE. THE PRESENT INVENTION RELATES TO A COMPOUND DERIVED FROM INDOLE, ESPECIALLY A THERAPEUTICALLY USEFUL COMPOUND, CHARACTERIZED IN THAT IT IS SELECTED FROM COMPOUNDS OF FORMULA (I) IN WHICH R1 REPRESENTS A HALOGEN OR A TRIFLUOROMETHYL GROUP, R2 REPRESENTS A HYDROGEN ATOM OR A C1-C4 ALKYL GROUP, R3 REPRESENTS AN ISOPROPYL (1-METHYLETHYL) GROUP OR A TERT-BUTYL (1,1-DIMETHYLETHYL) GROUP AND N=3 OR 4 AND PHARMACEUTICALLY ACCEPTABLE SALTS OF SAID COMPOUNDS OF FORMULA (I) APPLICATION: TREATMENT OF NEURODEGENERATIVE DISEASES AND MORE PARTICULARLY OF PARKINSON’S DISEASE.
