CHENG HENGMIAO,JOHNSON JR THEODORE OTTO,KATH JOHN CHARLES,LIU KEVIN KUN-CHIN,LUNNEY ELIZABETH ANN,NAGATA ASAKO,NAIR SAJIV KRISHNAN,PLANKEN SIMON PAUL,SUTTON SCOTT CHANNING
申请号:
IN1874/DELNP/2014
公开号:
IN2014DN01874A
申请日:
2014.03.11
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, T, V, W, X, Y, Z, ring A, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17 and m are defined herein. There novel pyrrolopyrimidine and purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.