Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof

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专利权人:

Peter R. Guzzo;Matthew D. Surman

发明人:

Matthew D. Surman,Peter R. Guzzo

申请号：

US13330989

公开号：

US08697700B2

申请日:

2011.12.20

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The present invention relates to piperazinone-substituted tetrahydrocarboline derivatives of formula (I):having the substituents as described herein which are melanin-concentrating hormone (MCH-1) receptor antagonists. The present invention also relates to pharmaceutical compositions including these compounds, and methods of preparation and use thereof.

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