COOK, DAVID D,MERRITT, JOHN J,NERIO, AILEEN A,RAPOPORT, HENRY H,STASSINOPOULOS, ADONIS A,WOLLOWITZ, SUSAN S,MATEJOVIC, JAN J,‧庫克,‧馬利特,‧耐裏歐,‧拉伯波特,‧斯塔西諾波洛斯,‧沃洛維茨,‧馬提約維克
申请号:
HK10109160.3
公开号:
HK1188441B
申请日:
2000.09.20
申请国别(地区):
HK
年份:
2014
代理人:
摘要:
Compounds and methods for inactivating pathogens in materials are described, including compositions and methods for inactivating pathogens in biological materials such as red blood cell preparations and plasma. The compounds and methods may be used to treat materials intended for in vitro or in vivo use, such as clinical testing or transfusion. The compounds are designed to specifically bind to and react with nucleic acid, and then to degrade to form breakdown products. The degradation reaction is preferably slower than the reaction with nucleic acid.