Screening method for the identification of inhibitors of HIV Tat methylation by the lysine methyltransferase Set7/9

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专利权人:

Melanie Ott

发明人:

Melanie Ott,Sara Pagans Lista

申请号：

US13230540

公开号：

US08580492B2

申请日:

2011.09.12

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention provides isolated methylated Tat peptides and compositions comprising the peptides. The present invention further provides isolated antibodies specific for a Lys-51-methylated Tat polypeptide. Also provided are methods of identifying agents that inhibit Lys-51 methylation of a Tat polypeptide. The present invention further provides methods of treating an immunodeficiency virus infection in a mammalian subject.

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中国工程科技知识中心

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http://www.ckcest.cn/home/