PARK, JUN DUK,박준덕,JI, JAI WOONG,지재웅,PARK, DONG CHAN,박동찬,PARK, JUN DUKKR,JI, JAI WOONGKR,PARK, DONG CHANKR
申请号：
KR1020130033126
公开号：
KR1020140118024A
申请日:
2013.03.27
申请国别(地区):
KR
年份:
2014
代理人:
摘要：
The present invention relates to a method for preparing injections of transfusion agent graduation of aqueous polysaccharides comprising beta-1,3-1,6-glucan as an active ingredient. The method comprises steps of: drying Keumsa Phellinus linteus spores and fruit body having excellent improvement of immunity activity and anticancer effect, sonicating or performing reflux extraction using 75% ethanol, performing centrifugation of the pretreated extracts of 13,000g for 10 minutes, performing hot water extraction by adding distilled water which is 5 times as much as the weight of a supernatant to the supernatant, and ultrafiltering the obtained aqueous extract and the sterilized distilled water having the weight of 10 times by a filter having molecular weight limitation of 10kD. Accordingly, the present invention has excellent improvement of immunity activity and anticancer effect compared to an existing oral powder formulation.본 발명은 면역활성 증가 및 항암 효과가 우수한 금사목질진흙버섯 포자 및 자실체를 건조한 후 초음파처리하거나 75% 에탄올로 환류추출을 수행하여 전처리한 추출물을 13,000g에서 10분간 원심분리한 후 상등액에 다시 상등액중량의 5배의 증류수를 가하여 열수추출하고 수득한 수용성 추출액을 10kD 분자량 한계를 가지는 필터로 10배 무게의 멸균증류수와 함께 한외여과하여 수득한 beta-1,3-1,6-glucan을 유효성분으로하는 수용성 다당체 수액제분획의 주사제의 제조방법과 비경구 주사제 항암용약제학적 조성물에 관한 것으로 종래 경구 섭취용 분말 제제에 비하여 면역활성 증가와 항암 효과가 뛰어나다.
