COMPOSÉS MACROCYCLIQUES ANTIBIOTIQUES ET LEURS PROCÉDÉS DE FABRICATION ET D'UTILISATION

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专利权人:

MERCK SHARP & DOHME CORP.

发明人:

申请号：

EP08855084.3

公开号：

EP2222309B1

申请日:

2008.11.28

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The invention encompasses an active metabolite of the 18-membered macrocyclic antimicrobial agents, specifically, a metabolite of tiacumicin B and in certain embodiments, R-Tiacumicin B or and its related compounds. In particular, the invention encompasses a compound that acts as a potent antibiotic agent for the treatment of bacterial infections, specifically GI infections caused by toxin producing strains of Clostridium difficile (C. difficile) and Clostridium perfringens (C. perfringens).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/