Michael J. Duryee;Geoffrey M. Thiele;Daniel R. Anderson
发明人:
Geoffrey M. Thiele,Daniel R. Anderson,Michael J. Duryee
申请号：
US14004514
公开号：
US20140170068A1
申请日:
2012.03.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
In various embodiments methods are provided for identifying a mammal having an elevated risk for an adverse cardiac event (e.g. an MI) and/or determining the prognosis for the mammal. In certain embodiments the methods comprise determining, or causing to be determined, the presence and/or level of antibodies that bind a malondialdehyde-acetaldehyde adduct (MAA adduct) in a biological sample from the mammal, where an elevated level of anti-MAA adduct antibodies, as compared to the level found in a normal healthy mammal is an indicator that that said mammal has one or more atherosclerotic lesions and/or is at elevated risk for a myocardial infarction.
