A system (100) for acquisition of biosignals from a subject, comprising: at least one biosensor (E) worn over a first location of a subject's body part and configured for biosignal measurement and providing a measured biosignal (BS1)； a plurality of inertial motion sensors (AC1 to ACN) worn over a plurality of locations of the subject's body part and configured for motion vector measurement and each providing a motion vector signal (MS1 to MSN), and wherein at least one of the plurality of inertial motion sensors is mechanically connected to the at least one biosensor； a biosignal adaptation unit (10) configured for receiving the measured biosignal (BS1) and adapting it into a digital measured biosignal (BS2)； a motion estimation unit (20) configured for receiving the motion vector signals from the plurality of inertial motion sensors and calculating a digital reference motion signal (RMS), wherein the digital reference motion signal is a relative motion vector signal indicating the relative motion of the at least one biosensor with respect to said first location of the subject's body part； and a digital filter unit (30) configured for performing removal of motion artifacts affecting the digital measured biosignal.
