Systems and methods are provided for fully automated image optimization based on automated organ recognition. In medical imaging systems, during medical imaging based on a particular imaging technique, an anatomical feature in an area being imaged may be automatically identifying, and based on the identifying of the anatomical feature, one or more imaging parameters or settings for optimizing imaging quality for the identified anatomical feature may be automatically determined. Imaging functions may then be configured based on the determined one or more imaging parameters or settings, and, based on processing of medical imaging dataset acquired based on that configuration, one or more medical images for rendering. A deep learning and/or neural network based model may be used in identifying the anatomical feature and selecting the one or more imaging parameters or settings.