Improved fluoresced imaging (FI) and other sensor data imaging processes, devices, and systems are provided to enhance display of FI images and reflected light images together. Generally an imaging scope device observes white light (WL) and FI images, and sends them to a control module which processes them for display together in an FI modality. A flashing mode causes temporal modulation of pixel intensity values of the FI image stream to improve distinguishability of features on the display. A composite image stream is produced depicting the reflected light components and the fluoresced light component detected by the image sensor assembly. Hardware designs are provided to enable real-time processing of image streams from medical scopes.