High efficiency FLP site-specific recombination in mammalian cells using an optimized FLP gene

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专利权人:

Christopher Raymond

发明人:

Christopher Raymond,Philippe Soriano

申请号：

US12307418

公开号：

US09206397B2

申请日:

2007.06.21

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention provides an optimized FLP site-specific recombinase coding sequence and methods for its use. This genetically engineered FLP gene displays a marked increase in recombination efficiency compared to the native FLP gene and is therefore useful in a wide array of molecular applications.

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