COMPOSITION FOR PREVENTING, IMPROVING OR TREATING OF T H1-MEDIATED IMMUNE DISEASE OR T H2-MEDIATED IMMUNE DISEASE COMPRISING EXTRACTS FROM LACTOBACILLUS CASEI AS AN ACTIVE INGREDIENTS
LEE, SO YOUNG,이소영,SHON, DONG HWA,손동화,SHIN, HEE SOON,신희순,LIM, SEONG IL,임성일,DO, JEONG RYONG,도정룡,JUNG, SUNG KEUN,정성근,CHUNG, MIN YU,정민유,EOM, JI EUN,엄지은,IM, SIN HYEOG,임신혁,LEE, SO YOUNGKR,SHON, DONG HWAKR,SHIN, HEE SOONKR,LIM, SEONG ILKR,DO, JEONG RYONGKR,JUNG, SUNG KEUNKR,CHUNG, MIN YUKR,EOM, JI EUNKR,IM, SIN HYEOGKR
申请号：
KR1020140087704
公开号：
KR1020160008059A
申请日:
2014.07.11
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
The present invention relates to a composition comprising Lactobacillus casei as an active ingredient for preventing, alleviating, or treating Th1-mediated immune diseases or Th2-mediated immune diseases. Lactobacillus casei of the present invention is capable of effectively controlling Th1-mediated immune diseases or Th2-mediated immune diseases, by activing control T cells, increasing generation of IL-10 which is anti-inflammatory cytokine, inhibiting generation IL-12 which is immune-activating cytokine, and reducing an amount of IgE antibodies produced. Therefore, the composition can be used as an anti-allergic composition and an anti-inflammatory composition.본 발명은 락토바실러스 카제이(Lactobacillus casei)를 유효성분으로 포함하는 Th1-매개 면역 질환 또는 Th2-매개 면역 질환의 예방, 개선 또는 치료용 조성물에 관한 것이다. 본 발명의 락토바실러스 카제이는 조절 T 세포를 활성화시키고, 항염증 사이토카인인 IL-10 생성을 증가시키며, 면역활성 사이토카인인 IL-12 생성을 억제시키며, IgE 항체의 생성양을 감소시킴으로써 Th1-매개 면역 질환 또는 Th2-매개 면역 질환을 효과적으로 제어하는바 항알레르기성 조성물 및 항염증성 조성물로 사용이 가능한 이점이 있다.
