Flygare, John A.,Pillow, Thomas H.,Safina, Brian,Verma, Visha,Wei, Binqing,Denny, William,Giddens, Anna,Lee, Ho,Lu, Guo-Liang,Miller, Christian,Rewcastle, Gordon,Tercel, Moana,Bonnet, Muriel
申请号:
AU2014307080
公开号:
AU2014307080A1
申请日:
2014.06.16
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The invention provides antibody-drug conjugates comprising an antibody conjugated to a 1-(chloromethyl)-2,3-dihydro-1H-benzo[e]indole (CBI) dimer drug moiety via a linker, and methods of using the antibody-drug conjugates.