John A. Flygare,Thomas H. Pillow,Brian Safina,Vishal Verma,BinQing Wei,William Denny,Anna Giddens,Ho Lee,Guo-Liang Lu,Christian Miller,Gordon Rewcastle,Moana Tercel,Muriel Bonnet
申请号:
US15182444
公开号:
US20160354485A1
申请日:
2016.06.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention provides antibody-drug conjugates comprising an antibody conjugated to a 1-(chloromethyl)-2,3-dihydro-1H-benzo[e]indole (CBI) dimer drug moiety via a linker, and methods of using the antibody-drug conjugates.