A therapeutic compress system for treatment of a body part. For treatment of the eye region, the compress system comprises a deformable frame that is disposable upon the eye region and includes a first frame section joined to a second frame section at a central bridge. A gel pack is removably joined to the frame and comprises a gelatinous material contained in a pouch. A V-strap assembly may be required for securing the gel pack and frame to the eye user in a manner that optimizes pressure of the gel pack on the eye region and comfort of the user. The compress system may include a gel impressor that is inwardly deformable so as to contact portions of the gel pack with the nasal corners of the eyes of the user.