BORRELLO, Ivan, M.,LEE, Susan,NOONAN, Kimberly, A.,PARDOLL, Drew, M.
申请号：
HK18114336
公开号：
HK1255208A1
申请日:
2018.11.09
申请国别(地区):
HK
年份:
2019
代理人:
摘要：
In some embodiments, marrow-infiltrating lymphocytes (“MILs”) comprising a chimeric antigen receptor (“CAR”) are provided. In some aspects, the embodiments relate to a method for making a recombinant MIL, comprising obtaining bone marrow comprising MILs； and transfecting, transforming, or transducing the MILs with a nucleic acid encoding a chimeric antigen receptor. In some aspects, the embodiments relate to a method for treating a condition in a subject, comprising administering to the subject a MIL comprising a CAR.
