This disclosure provides compositions, including Listeria delivery vectors comprising minigene expression constructs, and methods of using the same for inducing an immune response against an antigen-expressing tumor and for treating the same, and vaccinating against the same in subjects bearing the tumors.本文揭示提供組成物,其包括含有袖珍基因表現構築體的李斯特菌遞送載體,及使用該組成物誘導針對抗原表現性腫瘤的免疫反應及用於治療腫瘤,及於載有腫瘤的個體體內接種對抗腫瘤之用法。