VINCENT, MARK,FERGUSON, PETER J.,RYTELEWSKI, MATEUSZ
申请号：
EP12757450
公开号：
EP2683825A4
申请日:
2012.03.12
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Methods of treating cancer using antisense oligonucleotides directed against DNA double-strand break repair proteins such as BRCA2 or RAD51 are provided. The antisense oligonucleotides can be used alone, in tandem or in combination with other cancer therapies, in particular with therapies that lead to DNA damage, inhibition of DNA repair or inhibition of DNA synthesis, such as radiation, platinum drugs, alkylating agents, PARP inhibitors, or inhibitors of thymidylate synthase.
