ANGEL GUZMAN-PEREZ,BENJAMIN DAWSON STEVENS,GARY ERIK ASPNES,JEFFREY ALLEN PFEFFERKORN,KEVIN JAMES FILIPSKI,MARY THERESA DIDIUK,MEIHUA MIKE TU
申请号：
BR112013016033
公开号：
BR112013016033A2
申请日:
2011.12.09
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
