Gary Erik Aspnes,Mary Theresa Didiuk,Kevin James Filipski,Angel Guzman-Perez,Jeffrey Allen Pfefferkorn,Benjamin Dawson Stevens,Meihua Mike Tu
申请号：
US14561879
公开号：
US09056834B2
申请日:
2014.12.05
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides a compound of Formula (I)or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
