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CELL MEMBRANE COATED MAGNETIC NANOPARTICLES AND ASSAYS FOR IDENTIFICATION OF TRANSMEMBRANE PROTEIN-BINDING COMPOUNDS
专利权人:
The Board of Trustees of The University of Alabama
发明人:
Lukasz Ciesla,Yuping Bao
申请号:
US16523454
公开号:
US20200096503A1
申请日:
2019.07.26
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are nanostructures comprising a cell membrane-derived material comprising a target membrane protein; and one or more magnetic nanoparticles; wherein the cell membrane-derived material encapsulates the one or more magnetic nanoparticles. Also disclosed are methods of screening a sample for a binding agent, the method comprising contacting a sample comprising a binding agent with a nanostructure to form a mixture, the nanostructure comprising a cell membrane-derived material comprising a target membrane protein; and one or more magnetic nanoparticles; wherein the cell membrane-derived material encapsulates the one or more magnetic nanoparticles; and separating the nanostructure and any binding agent bound thereto from the mixture with a magnet.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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