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Regulatory element for heterologous protein production in the fruiting body of filamentous fungi
专利权人:
Intrexon Corporation
发明人:
Shi Zhixin,Wilkinson Jack Q.,Walters Donald S.,Romaine C. Peter
申请号:
US201514851819
公开号:
US10131916(B2)
申请日:
2015.09.11
申请国别(地区):
美国
年份:
2018
代理人:
McKee, Voorhees & Sease, PLC
摘要:
The present invention provides compositions and methods for regulating expression of nucleotide sequences in fungi. Compositions are novel nucleotide sequences for a tissue preferred promoter isolated from the Agaricus bisporus lectin gene. The sequences drive expression preferentially to fruit body tissue. A method for expressing a nucleotide sequence in fungi using the regulatory sequences disclosed herein is provided. The method comprises transforming a fungal cell to comprise a nucleotide sequence operably linked to one or more of the regulatory sequences of the present invention and regenerating a stably transformed fungus from the transformed cell.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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