Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins

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专利权人:

The Regents of the University of California

发明人:

James D. Marks,Maria Consuelo Garcia

申请号：

US14873071

公开号：

US09902780B2

申请日:

2015.10.01

申请国别(地区):

US

年份:

2018

代理人:

摘要：

This invention provides antibodies that specifically bind to and typically neutralize botulinum neurotoxins (e.g., BoNT/A, BoNT/B, BoNT/E, etc.) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism.

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中国工程科技知识中心

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