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Therapeutic Monoclonal Antibodies that Neutralize Botulinum Neurotoxins
专利权人:
James D. Marks
发明人:
James D. Marks,Peter Amersdorfer,Isin Geren,Jianlong Lou,Ali Razai,Maria Consuelo Garcia
申请号:
US13175628
公开号:
US20120177663A1
申请日:
2011.07.01
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention provides antibodies that specifically bind to and neutralize botulinum neurotoxin type A (BoNT/A) and the epitopes bound by those antibodies. The antibodies and derivatives thereof and/or other antibodies that specifically bind to the neutralizing epitopes provided herein can be used to neutralize botulinum neurotoxin and are therefore also useful in the treatment of botulism.
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