2,4-disubstituted phenylene-1,5-diamine derivatives and applications thereof, and pharmaceutical compositions and pharmaceutically acceptable compositions prepared therefrom
YANGTZE RIVER PHARMACEUTICAL GROUP CO. LTD.;SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO. LTD.
发明人:
Lan Jiong,Jin Yunzhou,Zhou Fusheng,Xie Jing,Shen Sida,Hu Yi,Liu Wei,Lv Qiang
申请号:
NZ72315115
公开号:
NZ723151A
申请日:
2015.02.13
申请国别(地区):
NZ
年份:
2018
代理人:
摘要:
The present invention provides a class of 2,4-disubstituted phenylene-1,5-diamine derivatives, having an inhibiting effect on EGFR tyrosine kinases, and pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug of said derivatives. See the description for the definitions of each group in the formula. In addition, the present invention also discloses pharmaceutical compositions, pharmaceutically acceptable compositions, and applications thereof.