2,4-DISUBSTITUTED PHENYLENE-1,5-DIAMINE DERIVATIVES AND APPLICATIONS THEREOF, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICALLY ACCEPTABLE COMPOSITIONS PREPARED THEREFROM

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专利权人:

YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD;SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO. LTD; LTD;YANGTZE RIVER PHARMACEUTICAL GROUP CO.

发明人:

LAN, JIONG,JIN, YUNZHOU,ZHOU, FUSHENG,XIE, JING,SHEN, SIDA,HU, YI,LIU, WEI,LV, QIANG

申请号：

PH12016501693

公开号：

PH12016501693A1

申请日:

2016.08.25

申请国别(地区):

PH

年份:

2016

代理人:

摘要：

The present invention provides a class of 2,4-disubstituted phenylene-1,5-diamine derivatives, having an inhibiting effect on EGFR tyrosine kinases, and pharmaceutically acceptable salt, stereoisomer, solvate, or prodrug of said derivatives. See the description for the definitions of each group in the formula. In addition, the present invention also discloses pharmaceutical compositions, pharmaceutically acceptable compositions, and applications thereof.

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